Indirubin-3′-monoxime-loaded PLGA-PEG nanoparticles for potential ...
Sep 1, 2022Nanoparticles have the capacity to cross the BBB through nanoparticle-mediated transport by endocytosis of brain capillary endothelial cells . Moreover, nanoparticulate drug carriers can protect drug molecules from premature release and degradation, improve the solubility of hydrophobic drugs, and promote the controlled and targeted release of drugs. Nanoparticles present low risk of toxicity ...